Novak Djokovic brushed aside Jo-Wilfried Tsonga 6-1 7-5 to set up a mouthwatering semi-final clash against home favourite Andy Murray.
Djokovic, who has never lost to Murray in a grand slam, looked to have the trickiest of the four quarter-finals at Wimbledon, but he made light work of Tsonga on Thursday afternoon, defeating the Frenchman 6-1 7-5 on Centre Court.
The world number two will meet Murray for the first time on grass on Friday after the British number one hammered Spain's Nicolas Almagro 6-4 6-1. Should Murray beat the Serb, he will be guaranteed his first Olympic medal.
Meanwhile, Serena Williams will face world number one Victoria Azarenka in the Olympic Games semi-finals after the Wimbledon champion destroyed Caroline Wozniacki's hopes on Court One with a command 6-0 6-3 win.
Zhang Jike completed the table tennis Grand Slam as Wang Hao endured more Olympics heartache at the London 2012 Games. Wang had ended with silver at the two previous showpieces, in Beijing 2008 and Athens 2004.
And the 28-year-old failed to go one step further again, meaning he will likely end his glittering career without winning all of table tennis' biggest prizes. It was 22-year-old Zhang who came out on top, romping to a 4-1 (18-16, 11-5, 11-5, 10-12, 13-11) success.
Elsewhere, Ki Bo Bae has returned the women's archery gold to South Korea after edging a one-arrow shoot-off with Mexico's Aida Roman at Lord's.
Ki, the top seed and world number two, was pushed all the way by the unfancied Roman and after drawing 5-5 across five sets, the Olympic title was decided one shot apiece. Ki drew first and hit a disappointing eight that crept high, but with nine needed to complete a huge upset Roman's arrow veered left and ended further out in the eight ring.
In the men's under-100kgs judo, Tagir Khaibulaev of Russia defeated Mongolian Tuvshinbayar Naidan to claim gold. The bronze medals went to Henk Grol, the number two seed, of Holland, delighting the massed ranked of Oranje in the stands. Defeated semi-finalist German Dimitri Peters, who knocked Grol out in the last eight, also won bronze.
Meanwhile, Vasyl Lomachenko showed the skills that have seen him routinely feted as the best amateur boxer in the world as he got his quest for a second Olympic title under way with a 15-3 victory over the Dominican Republic's Wellington Romero.